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EPA Region 6 (South Central)

Serving Arkansas, Louisiana, New Mexico, Oklahoma, Texas and 66 Tribal Nations

A lake in Texas.

Map of EPA Region 6

ArkansasLouisianaNew MexicoOklahomaTexas

Learn more about our work in Arkansas, Louisiana, New Mexico, Oklahoma, Texas and with 66 tribal nations

Region 6 News Releases

  • HF Sinclair Navajo Agrees to Settlement to Reduce Climate- and Health Harming Emissions at Artesia Refinery in New Mexico

  • EPA Announces $300,000 in Funding to Three Small Businesses in Texas and Oklahoma for the Development of Environmental Technologies

  • Biden-Harris Administration Announces $40 Million in Environmental and Climate Justice Community Change Grants for Louisiana Organizations

  • Biden-Harris Administration Announces Over $12 Million to Livingston and Jefferson Parish for Clean Heavy-Duty Vehicles as Part of Investing in America Agenda

  • Biden-Harris Administration Announces Over $62 Million to North Central Texas Council of Governments and Dallas Independent School District for Clean Heavy-Duty Vehicles as Part of Investing in America Agenda

Emergency Response

  • National Response Center

If you are seeing an environmental event that may lead to an immediate threat to human health or the environment, call 911 and then report it to the National Response Center at 1-800-424-8802.

  • EPA's role in Emergency Responses
  • Emergency response and removal sites in my community

Preparing for Natural Disasters

  • Natural disasters
  • Prepare for a hurricane
  • Prepare for flooding
  • Información en español

Key Issues

  • EPA Region 6 Comments on Proposed LDEQ Air Permit for Atalco Alumina – Gramercy Operations (pdf) (1.29 MB)
  • Region 6 Delivers - EPA's Work in Laredo (pdf) (482.19 KB)
  • Stronger Engagement for Results in Justice
  • Ethylene Oxide in Texas
  • Ethylene Oxide in Louisiana
  • Illinois River Watershed
  • Waste Isolation Pilot Plant (WIPP)
  • Chloroprene in LaPlace, Louisiana

Public Notices, Meetings and Events

Find public notices and information on meetings and events in Arkansas, Louisiana, New Mexico, Oklahoma and Texas. 

Region 6 Delivers

  • Region 6 2024 Accomplishments Report (pdf) (3.62 MB)
  • Region 6 Delivers - EPA's Work in Laredo (pdf) (482.19 KB)
  • R6 Delivers-Louisiana and the Mississippi River Industrial Corridor (pdf) (680.92 KB)

Related Information

  • General Phone information
    800-887-6063
    214-665-2200 (Outside of Region 6)
  • Organization chart
  • Region 6's Laboratory
  • U.S. – Mexico Border Program
  • Visiting Region 6
  • Follow us on X
  • Visit us on Facebook
  • Contact Region 6

Mailing Addresses

EPA Region 6 Main Office
1201 Elm Street, Suite 500
Dallas, Texas 75270
800-887-6063
214-665-2200 (Outside of Region 6)

Houston Laboratory
10625 Fallstone Road
Houston, TX 77099
281-983-2100

El Paso Border Office
511 E. San Antonio, Suite 145
El Paso, TX 79901
915-533-7273

Oklahoma Field Office
US EPA
1645 South 101 East Avenue
Room 134
Tulsa OK 74128-4629

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Contact EPA
Contact EPA to ask a question, provide feedback, or report a problem.
Last updated on January 17, 2025
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