ETAP July 11-12, 2023 Meeting

Please visit the Federal Register Notice for more information, including in-person and virtual registration instructions and public comment opportunities.

Meeting Materials

• Agenda - ETAP July 2023 (pdf) (119.69 KB)
• Meeting Minutes (pdf) (557.82 KB)
• Standard Methods for Development of ETAPs (pdf) (3.08 MB)
• Scientific Studies Supporting Development of Transcriptomic Points of Departure for EPA Transcriptomic Assessment Products (ETAPs) (pdf) (2.27 MB)
• BOSC Portfolio Approach (pdf) (1.2 MB)
• ETAP Introduction Day 1 (pdf) (2.05 MB)
• ETAP Scientific Support (pdf) (4.54 MB)
• ETAP Literature Search (pdf) (6.17 MB)
• Overview of the NTP Approach to Genomic Dose-Response (GDR) Modeling Report (pdf) (1.56 MB)
• Dose Response Methods & Parameter Refinement (pdf) (917.79 KB)
• BMD Concordance Analysis with Inter-study Variability (pdf) (822.61 KB)
• Summary of Scientific Studies Supporting Development of Transcriptomic Points of Departure for ETAPs (pdf) (737.84 KB)
• Database Search and Systematic Evidence Map (SEM) (pdf) (1.13 MB)
• EPA Transcriptomic Assessment Product Study Overview (pdf) (809.98 KB)
• Transcriptomic Dose Response Analysis (pdf) (811.08 KB)
• Transcriptomic Reference Value (TRV) Derivation and Reporting (pdf) (730.12 KB)
• Comparison of Transcriptomic Reference Doses (TRVs) with Reference Doses/Concentrations (RfD/Cs) and Summary (pdf) (1.32 MB)
• BOSC ETAP Final Report (pdf) (1.68 MB)