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  2. Pesticide Registration

Pesticide Registration Manual

The Pesticide Registration Manual is a resource for companies and individuals who want to have their pesticide products registered for sale in the United States. The manual describes the EPA's review and decision-making process for registering a pesticide product and its use. Detailed information for pesticide registrants (the company or individual applying to register a pesticide) concerning their responsibilities before, during and after the review process is also included in the manual.

 
Title PDF
Introduction Registration Manual: Introduction (pdf) (186.6 KB)
How to Register a Pesticide Product – A Guide for Applicants New to the Process  Registration Manual: How to Register a Pesticide (pdf) (304.61 KB)
Chapter 1: Requirements for Pesticide Registration and Registrant Obligations Registration Manual: Chapter 1 (pdf) (337.72 KB)
Chapter 2: Registering a Pesticide Product Registration Manual: Chapter 2 (pdf) (447.9 KB)
Chapter 3: Additional Considerations for Biopesticide Products Registration Manual: Chapter 3 (pdf) (413.29 KB)
Chapter 4: Additional Considerations for Antimicrobial Products Registration Manual: Chapter 4 (pdf) (411.29 KB)
Chapter 5: Registration Fees Registration Manual: Chapter 5 (pdf) (291.84 KB)
Chapter 6: Amending a Registered Pesticide Product Registration Manual: Chapter 6 (pdf) (267.71 KB)
Chapter 7: Notifications and Minor Formulation Amendments Registration Manual: Chapter 7 (pdf) (307.08 KB)
Chapter 8: Inert Ingredients Registration Manual: Chapter 8 (pdf) (213.9 KB)
Chapter 9: Supplemental Distribution of a Registered Pesticide Registration Manual: Chapter 9 (pdf) (199.93 KB)
Chapter 10: Data Compensation Requirements Registration Manual: Chapter 10 (pdf) (397.93 KB)
Chapter 11: Tolerance Petitions Registration Manual: Chapter 11 (pdf) (280.79 KB)
Chapter 12: Applying for an Experimental Use Permit Registration Manual: Chapter 12 (pdf) (268.11 KB)
Chapter 13: Devices Registration Manual: Chapter 13 (pdf) (305.49 KB)
Chapter 14: How to Obtain an EPA Company or Establishment Number and Change of Address of Contact Information Registration Manual: Chapter 14 (pdf) (240.49 KB)
Chapter 15: Submitting Data and Confidential Business Information Registration Manual: Chapter 15 (pdf) (232.24 KB)
Chapter 16: Transfer of Product Registrations and Data Rights Registration Manual: Chapter 16 (pdf) (264.02 KB)
Chapter 17: State Regulatory Authority Registration Manual: Chapter 17 (pdf) (236.98 KB)
Chapter 18: Other Federal or State Agency Requirements Registration Manual: Chapter 18 (pdf) (305.27 KB)
Chapter 19: How to Obtain Publications Registration Manual: Chapter 19 (pdf) (205.22 KB)
Chapter 20: Forms and How to Obtain Them Registration Manual: Chapter 20 (pdf) (226.93 KB)
Chapter 21: Directions for Submitting Applications and Contacting EPA Registration Manual: Chapter 21 (pdf) (318.05 KB)
Appendix A: Guidance Documents Registration Manual: Appendix A (pdf) (129.13 KB)
Appendix B: Examples of Registrant Documents Registration Manual: Appendix B (pdf) (132.98 KB)
Appendix C: Pesticide Forms Overview Table Registration Manual: Appendix C (pdf) (161.09 KB)
Appendix D: Examples of Completed Forms Registration Manual: Appendix D (pdf) (140.38 KB)

EPA Contacts for Support

  • Conventional Chemicals
    OPP RD Ombudsman
    (opp_rd_ombudsman@epa.gov)
  • PRIA Ombudsman
    Stephen Schaible
    (schaible.stephen@epa.gov)
    (202) 566-1261
  • Antimicrobial Chemicals
    pesticidequestions@epa.gov
  • Biopesticide Chemicals
    BPPDQuestions
    (bppdquestions@epa.gov) 

Helpful Resources

  • Data Requirements Checklist
  • Label Review Manual
  • Registration Forms
  • Reduced Risk Pesticides
  • Cover Letter Suggestions for Notifications and Fast-Track Amendment Action Final (pdf) (172.62 KB)
  • Common Reasons a Notification May Be Rejected (pdf) (144.08 KB)
  • Common Product Chemistry and Acute Toxicity Deficiencies (pdf) (189.86 KB)

Comments or technical issues about the Registration Manual? Email us.

Contact Us about Pesticide Registration to ask a question, provide feedback, or report a problem.
Last updated on October 23, 2024
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